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Anxious times await biggies

REUTERS, London
The stakes are high for former European champions Manchester United, Porto and AC Milan in this week's penultimate round of Champions League group matches.
All three are making heavy weather of reaching the last 16 with Porto facing certain elimination if they lose at home to Scottish champions Rangers in Group H on Wednesday.
A loss for United at home to Villarreal on Tuesday, combined with a victory for Lille over Benfica, will leave them scrapping for nothing more than a UEFA Cup place from Group D.
AC Milan face a testing night in Istanbul on Wednesday against Fenerbahce where defeat would leave the six-time European champions struggling to emerge from a tight Group E.
Nerves are less fraught for some of Europe's other big guns with holders Liverpool and Group G rivals Chelsea both set to book their places in the last 16 on Wednesday.
Four clubs -- Barcelona, Arsenal, Olympique Lyon and Real Madrid -have already qualified for the knock-
out phase.
Liverpool need just a point at home to Real Betis while English champions Chelsea will move through to the next round with victory over pointless Anderlecht.
Juventus and Bayern Munich can also take their places in the last 16 in home matches against Club Brugge and Rapid Vienna respectively in Group A.
Juve need just a point while Bayern will go through with a victory as long as the Italians do not lose to Brugge.
Unsettled midfielder Michael Ballack is likely to miss Bayern's clash against bottom club Rapid with a thigh injury suffered in Germany's friendly against France.
Four-time winners Ajax are one Group B victory away from the knockout phase and should manage that against Sparta Prague, while Inter Milan need just a point against Artmedia Bratislava to emerge from Group H.
PSV Eindhoven are also in pole position in Group E and will clinch a top-two berth with victory at Schalke on Wednesday, irrespective of how Milan fare against Fenerbahce.
Philip Cocu is doubtful after missing the weekend's 4-4 draw at RKC Waalwijk while American DaMarcus Beasley is ruled out with a
hamstring injury.
Porto, who were crowned champions of Europe under Jose Mourinho in 2004, travel to Glasgow desperate for a victory that would revive their flagging campaign.
Bottom with three points, Porto will hope to benefit from the pressure building on Rangers manager Alex McLeish after a 3-0 defeat by archrivals Celtic left them hopelessly adrift in the Scottish Premier League at the weekend.
Porto will also take heart from the absence of Rangers' Croatian striker Dado Prso who damaged a hamstring in the morale-sapping defeat at Celtic Park.
Manchester United manager Alex Ferguson describes Tuesday's home match against Villarreal as "one of the most important in the Europe for us over the last few years".
It is 10 years since United failed to progress from the group stage, although with Villarreal's Argentine playmaker Juan Roman Riquelme missing with a thigh injury the underpressure Scot should sleep a little easier.
"I am depending and trusting on our home form to get us through," said Ferguson.
"Our home form in the group stages over the years has been terrific
and it has to be like that on Tuesday because Villarreal are a very good side."
Milan's unease at a return to Istanbul, scene of their astonishing final defeat by Liverpool in May, will not have been placated by a 3-1 loss to Fiorentina in Serie A on Sunday.
"Fortunately, we have the chance to make up for this defeat when we play against Fenerbahce on Wednesday, " said disappointed Milan coach Carlo Ancelotti.
They have lost on two of three visits to Turkey to face Turkish opposition, although Fenerbahce themselves have a dire record against Italian clubs, losing eight of the nine games they have played against them.
Wednesday's Group F clash between group leaders Olympique Lyon and Real Madrid in the Bernabeu will give the Spanish club the perfect chance to erase the memory of Saturday's 3-0 defeat by bitter rivals Barcelona at the Bernabeu.
Top spot is up for grabs while Real striker Raul can become the first player to make 100 appearances in the Champions League since it began in 1992, if he starts. The Madrid captain picked up a knee injury against Barca and will have tests on Monday.